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Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH
KEY POINTS: Cl(−) and HCO(3) (−) had similar paracellular permeabilities in human airway epithelia. P(Cl)/P(Na) of airway epithelia was unaltered by pH 7.4 vs. pH 6.0 solutions. Under basal conditions, calculated paracellular HCO(3) (−) flux was secretory. Cytokines that increased airway surface liq...
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| Veröffentlicht in: | J Physiol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7589346/ https://ncbi.nlm.nih.gov/pubmed/32627187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280120 |
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