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Acidic pH increases airway surface liquid viscosity in cystic fibrosis

Cystic fibrosis (CF) disrupts respiratory host defenses, allowing bacterial infection, inflammation, and mucus accumulation to progressively destroy the lungs. Our previous studies revealed that mucus with abnormal behavior impaired mucociliary transport in newborn CF piglets prior to the onset of s...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Tang, Xiao Xiao, Ostedgaard, Lynda S., Hoegger, Mark J., Moninger, Thomas O., Karp, Philip H., McMenimen, James D., Choudhury, Biswa, Varki, Ajit, Stoltz, David A., Welsh, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767348/
https://ncbi.nlm.nih.gov/pubmed/26808501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83922
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