Acidic pH increases airway surface liquid viscosity in cystic fibrosis

Cystic fibrosis (CF) disrupts respiratory host defenses, allowing bacterial infection, inflammation, and mucus accumulation to progressively destroy the lungs. Our previous studies revealed that mucus with abnormal behavior impaired mucociliary transport in newborn CF piglets prior to the onset of s...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tang, Xiao Xiao, Ostedgaard, Lynda S., Hoegger, Mark J., Moninger, Thomas O., Karp, Philip H., McMenimen, James D., Choudhury, Biswa, Varki, Ajit, Stoltz, David A., Welsh, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767348/
https://ncbi.nlm.nih.gov/pubmed/26808501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83922
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