Acidic pH increases airway surface liquid viscosity in cystic fibrosis

Cystic fibrosis (CF) disrupts respiratory host defenses, allowing bacterial infection, inflammation, and mucus accumulation to progressively destroy the lungs. Our previous studies revealed that mucus with abnormal behavior impaired mucociliary transport in newborn CF piglets prior to the onset of s...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Tang, Xiao Xiao, Ostedgaard, Lynda S., Hoegger, Mark J., Moninger, Thomas O., Karp, Philip H., McMenimen, James D., Choudhury, Biswa, Varki, Ajit, Stoltz, David A., Welsh, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767348/
https://ncbi.nlm.nih.gov/pubmed/26808501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83922
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