ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

ONC201 was originally discovered as TNF-Related Apoptosis Inducing Ligand (TRAIL)-inducing compound TIC10. ONC201 appears to act as a selective antagonist of the G protein coupled receptor (GPCR) dopamine receptor D2 (DRD2), and as an allosteric agonist of mitochondrial protease caseinolytic proteas...

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Xehetasun bibliografikoak
Argitaratua izan da:Neoplasia
Egile Nagusiak: Prabhu, Varun Vijay, Morrow, Sara, Rahman Kawakibi, Abed, Zhou, Lanlan, Ralff, Marie, Ray, Jocelyn, Jhaveri, Aakash, Ferrarini, Isacco, Lee, Young, Parker, Cassandra, Zhang, Yiqun, Borsuk, Robyn, Chang, Wen-I, Honeyman, Joshua N., Tavora, Fabio, Carneiro, Benedito, Raufi, Alexander, Huntington, Kelsey, Carlsen, Lindsey, Louie, Anna, Safran, Howard, Seyhan, Attila A., Tarapore, Rohinton S., Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, El-Deiry, Wafik S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Neoplasia Press 2020
Gaiak:
Review article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588802/
https://ncbi.nlm.nih.gov/pubmed/33142238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.09.005
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