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Discovery and clinical introduction of first-in-class imipridone ONC201
ONC201 is the founding member of a novel class of anti-cancer compounds called imipridones that is currently in Phase II clinical trials in multiple advanced cancers. Since the discovery of ONC201 as a p53-independent inducer of TRAIL gene transcription, preclinical studies have determined that ONC2...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342060/ https://ncbi.nlm.nih.gov/pubmed/27602582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11814 |
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