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Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

Filoviruses such as Ebola and Marburg virus bud from the host membrane as enveloped virions. This process is achieved by the matrix protein VP40. When expressed alone, VP40 induces budding of filamentous virus-like particles, suggesting that localization to the plasma membrane, oligomerization into...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Wan, William, Clarke, Mairi, Norris, Michael J, Kolesnikova, Larissa, Koehler, Alexander, Bornholdt, Zachary A, Becker, Stephan, Saphire, Erica Ollmann, Briggs, John AG
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588233/
https://ncbi.nlm.nih.gov/pubmed/33016878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59225
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