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Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

Filoviruses such as Ebola and Marburg virus bud from the host membrane as enveloped virions. This process is achieved by the matrix protein VP40. When expressed alone, VP40 induces budding of filamentous virus-like particles, suggesting that localization to the plasma membrane, oligomerization into...

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Vydáno v:eLife
Hlavní autoři: Wan, William, Clarke, Mairi, Norris, Michael J, Kolesnikova, Larissa, Koehler, Alexander, Bornholdt, Zachary A, Becker, Stephan, Saphire, Erica Ollmann, Briggs, John AG
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588233/
https://ncbi.nlm.nih.gov/pubmed/33016878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59225
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