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Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

Filoviruses such as Ebola and Marburg virus bud from the host membrane as enveloped virions. This process is achieved by the matrix protein VP40. When expressed alone, VP40 induces budding of filamentous virus-like particles, suggesting that localization to the plasma membrane, oligomerization into...

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Pubblicato in:eLife
Autori principali: Wan, William, Clarke, Mairi, Norris, Michael J, Kolesnikova, Larissa, Koehler, Alexander, Bornholdt, Zachary A, Becker, Stephan, Saphire, Erica Ollmann, Briggs, John AG
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588233/
https://ncbi.nlm.nih.gov/pubmed/33016878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59225
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