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Quinoxaline-based inhibitors of Ebola and Marburg VP40 egress
We prepared a series of quinoxalin-2-mercapto-acetyl-urea analogs and evaluated them for their ability to inhibit viral egress in our Marburg and Ebola VP40 VLP budding assays in HEK293T cells. We also evaluated selected compounds in our bimolecular complementation assay (BiMC) to detect and visuali...
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| Udgivet i: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955528/ https://ncbi.nlm.nih.gov/pubmed/27377328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.06.053 |
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