APOE2 is associated with longevity independent of Alzheimer’s disease

Although the ε2 allele of apolipoprotein E (APOE2) benefits longevity, its mechanism is not understood. The protective effects of the APOE2 on Alzheimer’s disease (AD) risk, particularly through their effects on amyloid or tau accumulation, may confound APOE2 effects on longevity. Herein, we showed...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Shinohara, Mitsuru, Kanekiyo, Takahisa, Tachibana, Masaya, Kurti, Aishe, Shinohara, Motoko, Fu, Yuan, Zhao, Jing, Han, Xianlin, Sullivan, Patrick M, Rebeck, G William, Fryer, John D, Heckman, Michael G, Bu, Guojun
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588231/
https://ncbi.nlm.nih.gov/pubmed/33074098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62199
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge