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APOE2 eases cognitive decline during aging: clinical and preclinical evaluations

OBJECTIVE: Apolipoprotein E (apoE), a major cholesterol carrier in the brain, is associated with a strong risk for Alzheimer’s disease. Compared to the risky APOE4 gene allele, the effects of the protective APOE2 gene allele are vastly understudied, and thus, need to be further clarified. METHODS: W...

詳細記述

保存先:
書誌詳細
出版年:Ann Neurol
主要な著者: Shinohara, Mitsuru, Kanekiyo, Takahisa, Yang, Longyu, Linthicum, Duane, Shinohara, Motoko, Fu, Yuan, Price, Laura, Frisch-Daiello, Jessica L., Han, Xianlin, Fryer, John D., Bu, Guojun
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010530/
https://ncbi.nlm.nih.gov/pubmed/26933942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24628
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