APOE2 eases cognitive decline during aging: clinical and preclinical evaluations

OBJECTIVE: Apolipoprotein E (apoE), a major cholesterol carrier in the brain, is associated with a strong risk for Alzheimer’s disease. Compared to the risky APOE4 gene allele, the effects of the protective APOE2 gene allele are vastly understudied, and thus, need to be further clarified. METHODS: W...

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Detaylı Bibliyografya
Yayımlandı:Ann Neurol
Asıl Yazarlar: Shinohara, Mitsuru, Kanekiyo, Takahisa, Yang, Longyu, Linthicum, Duane, Shinohara, Motoko, Fu, Yuan, Price, Laura, Frisch-Daiello, Jessica L., Han, Xianlin, Fryer, John D., Bu, Guojun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010530/
https://ncbi.nlm.nih.gov/pubmed/26933942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24628
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