APOE2 eases cognitive decline during aging: clinical and preclinical evaluations

OBJECTIVE: Apolipoprotein E (apoE), a major cholesterol carrier in the brain, is associated with a strong risk for Alzheimer’s disease. Compared to the risky APOE4 gene allele, the effects of the protective APOE2 gene allele are vastly understudied, and thus, need to be further clarified. METHODS: W...

Full description

Saved in:
Bibliographic Details
Published in:Ann Neurol
Main Authors: Shinohara, Mitsuru, Kanekiyo, Takahisa, Yang, Longyu, Linthicum, Duane, Shinohara, Motoko, Fu, Yuan, Price, Laura, Frisch-Daiello, Jessica L., Han, Xianlin, Fryer, John D., Bu, Guojun
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010530/
https://ncbi.nlm.nih.gov/pubmed/26933942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24628
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items