Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline

Malaria, despite many efforts, remains among the most problematic infectious diseases worldwide, mainly due to the development of drug resistance by Plasmodium falciparum. The antibiotic fosmidomycin (FSM) is also known for its antimalarial activity by targeting the non-mevalonate isoprenoid synthes...

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Vydáno v:Molecules
Hlavní autoři: Palla, Despina, Antoniou, Antonia I., Baltas, Michel, Menendez, Christophe, Grellier, Philippe, Mouray, Elisabeth, Athanassopoulos, Constantinos M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587979/
https://ncbi.nlm.nih.gov/pubmed/33096817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204858
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