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Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase
With the aim to clarify the mechanism(s) of action of nitroaromatic compounds against the malaria parasite Plasmodium falciparum, we examined the single-electron reduction by P. falciparum ferredoxin:NADP(+) oxidoreductase (PfFNR) of a series of nitrofurans and nitrobenzenes (n = 23), and their abil...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6943496/ https://ncbi.nlm.nih.gov/pubmed/31835450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244509 |
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