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Synthesis and Antiplasmodial Activity of Novel Fosmidomycin Derivatives and Conjugates with Artemisinin and Aminochloroquinoline

Malaria, despite many efforts, remains among the most problematic infectious diseases worldwide, mainly due to the development of drug resistance by Plasmodium falciparum. The antibiotic fosmidomycin (FSM) is also known for its antimalarial activity by targeting the non-mevalonate isoprenoid synthes...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Palla, Despina, Antoniou, Antonia I., Baltas, Michel, Menendez, Christophe, Grellier, Philippe, Mouray, Elisabeth, Athanassopoulos, Constantinos M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587979/
https://ncbi.nlm.nih.gov/pubmed/33096817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204858
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