Peroxide Bond-Dependent Antiplasmodial Specificity of Artemisinin and OZ277 (RBx11160)

Using nonperoxidic analogs of artemisinin and OZ277 (RBx11160), the strong in vitro antiplasmodial activities of the latter two compounds were shown to be peroxide bond dependent. In contrast, the weak activities of artemisinin and OZ277 against six other protozoan parasites were peroxide bond indep...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kaiser, Marcel, Wittlin, Sergio, Nehrbass-Stuedli, Angela, Dong, Yuxiang, Wang, Xiaofang, Hemphill, Andrew, Matile, Hugues, Brun, Reto, Vennerstrom, Jonathan L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Mechanisms of Action: Physiological Effects
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932508/
https://ncbi.nlm.nih.gov/pubmed/17562801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00225-07
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