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In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains

BACKGROUND: Semi-synthetic artemisinin derivatives are powerful peroxidic drugs in artemisinin-based combination therapy (ACT) recommended as first-line treatment of Plasmodium falciparum malaria in disease-endemic countries. Studies by Eckstein-Ludwig and co-workers showed both thapsigargin and art...

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Detalhes bibliográficos
Main Authors: Abiodun, Oyindamola O, Brun, Reto, Wittlin, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566918/
https://ncbi.nlm.nih.gov/pubmed/23368889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-43
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