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Nonribosomal Peptides Produced by Minimal and Engineered Synthetases with Terminal Reductase Domains
Nonribosomal peptide synthetases (NRPSs) use terminal reductase domains for 2‐electron reduction of the enzyme‐bound thioester releasing the generated peptides as C‐terminal aldehydes. Herein, we reveal the biosynthesis of a pyrazine that originates from an aldehyde‐generating minimal NRPS termed AT...
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| Publicado en: | Chembiochem |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586950/ https://ncbi.nlm.nih.gov/pubmed/32378773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000176 |
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