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The Down-Regulation of Clusterin Expression Enhances the αSynuclein Aggregation Process

Parkinson’s Disease (PD) is a progressive neurodegenerative disease characterized by the presence of proteinaceous aggregates of αSynuclein (αSyn) in the dopaminergic neurons. Chaperones are key components of the proteostasis network that are able to counteract αSyn’s aggregation, as well as its tox...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Lenzi, Chiara, Ramazzina, Ileana, Russo, Isabella, Filippini, Alice, Bettuzzi, Saverio, Rizzi, Federica
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582711/
https://ncbi.nlm.nih.gov/pubmed/33003328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197181
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