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EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism
The proteasome inhibitors Bortezomib (BZM) and MG132 trigger cancer cell death via induction of endoplasmic reticulum (ER) stress and unfolded protein response. Epigallocatechin gallate (EGCG), the most bioactive green tea polyphenol, is known to display strong anticancer properties as it inhibits p...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607952/ https://ncbi.nlm.nih.gov/pubmed/26471237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15270 |
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