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EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism
The proteasome inhibitors Bortezomib (BZM) and MG132 trigger cancer cell death via induction of endoplasmic reticulum (ER) stress and unfolded protein response. Epigallocatechin gallate (EGCG), the most bioactive green tea polyphenol, is known to display strong anticancer properties as it inhibits p...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607952/ https://ncbi.nlm.nih.gov/pubmed/26471237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15270 |
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