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Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism

Clusterin (CLU) is a stress-activated glycoprotein, whose expression is altered both in inflammation and cancer. Previously, we showed that abrogation of CLU expression in cancer-prone mice (TRAMP) results in the enhancement of tumor spreading and homing, concomitant with an enhanced expression of N...

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Detalhes bibliográficos
Publicado no:J Oncol
Main Authors: Bonacini, Martina, Negri, Aide, Davalli, Pierpaola, Naponelli, Valeria, Ramazzina, Ileana, Lenzi, Chiara, Bettuzzi, Saverio, Rizzi, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925831/
https://ncbi.nlm.nih.gov/pubmed/31885575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4081624
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