Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity

Engineered allosteric regulation of protein activity provides significant advantages for the development of robust and broadly applicable tools. However, the application of allosteric switches in optogenetics has been scarce and suffers from critical limitations. Here, we report an optogenetic appro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Shaaya, Mark, Fauser, Jordan, Zhurikhina, Anastasia, Conage-Pough, Jason E, Huyot, Vincent, Brennan, Martin, Flower, Cameron T, Matsche, Jacob, Khan, Shahzeb, Natarajan, Viswanathan, Rehman, Jalees, Kota, Pradeep, White, Forest M, Tsygankov, Denis, Karginov, Andrei V
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2020
विषय:
Biochemistry and Chemical Biology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577742/
https://ncbi.nlm.nih.gov/pubmed/32965214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60647
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