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Phosphorylation alters Bim-mediated Mcl-1 stabilization and priming

Mcl-1 is a highly labile protein, subject to extensive posttranslational regulation. This distinguishes Mcl-1 from other anti-apoptotic proteins and necessitates further study to better understand how interactions with pro-apoptotic Bcl-2 proteins affect its regulation. One such protein, Bim, is kno...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Conage-Pough, Jason E., Boise, Lawrence H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215700/
https://ncbi.nlm.nih.gov/pubmed/29775995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14505
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