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Bone marrow microenvironment–derived signals induce Mcl-1 dependence in multiple myeloma
Multiple myeloma is highly dependent on the bone marrow microenvironment until progressing to very advanced extramedullary stages of the disease such as plasma cell leukemia. Stromal cells in the bone marrow secrete a variety of cytokines that promote plasma cell survival by regulating antiapoptotic...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5383873/ https://ncbi.nlm.nih.gov/pubmed/28151428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-745059 |
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