Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis

Podosomes are compartmentalized actin-rich adhesions, defined by their ability to locally secrete proteases and remodel extracellular matrix. Matrix remodeling by endothelial podosomes facilitates invasion and thereby vessel formation. However, the mechanisms underlying endothelial podosome formatio...

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Publicat a:J Cell Biol
Autors principals: Collins, Kerrie B., Kang, Hojin, Matsche, Jacob, Klomp, Jennifer E., Rehman, Jalees, Malik, Asrar B., Karginov, Andrei V.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041690/
https://ncbi.nlm.nih.gov/pubmed/31865373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201903023
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