Time variant SRC kinase activation determines endothelial permeability response

In the current model of endothelial barrier regulation, the tyrosine kinase SRC is purported to induce disassembly of endothelial adherens junctions (AJs) via phosphorylation of VE cadherin, and thereby increase junctional permeability. Here, using a chemical biology approach to temporally control S...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Klomp, Jennifer E., Shaaya, Mark, Matsche, Jacob, Rebiai, Rima, Aaron, Jesse S., Collins, Kerrie B., Huyot, Vincent, Gonzalez, Annette M., Muller, William A., Chew, Teng-Leong, Malik, Asrar B., Karginov, Andrei V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697609/
https://ncbi.nlm.nih.gov/pubmed/31130521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.04.007
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