Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae

Caveolin 1 (Cav1) is a required structural component of caveolae, and its phosphorylation by Src is associated with an increase in caveolae-mediated endocytosis. Here we demonstrate, using quantitative live-cell 4D, TIRF, and FRET imaging, that endocytosis and trafficking of caveolae are associated...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Zimnicka, Adriana M., Husain, Yawer S., Shajahan, Ayesha N., Sverdlov, Maria, Chaga, Oleg, Chen, Zhenlong, Toth, Peter T., Klomp, Jennifer, Karginov, Andrei V., Tiruppathi, Chinnaswamy, Malik, Asrar B., Minshall, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927282/
https://ncbi.nlm.nih.gov/pubmed/27170175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-11-0756
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