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Targeting of Nanoparticle-Complexed Drugs across the Vascular Endothelial Barrier via Caveolae

The endothelial cell monolayer lining the vessel wall forms a size-selective, semi-permeable barrier between the blood and tissue that must be crossed by blood borne therapeutic agents to reach diseased extravascular tissue. Nanoparticles engineered to carry drugs present an opportunity to enhance t...

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Detalhes bibliográficos
Main Authors: Wang, Zhenjia, Tiruppathi, Chinnaswamy, Cho, Jaehyung, Minshall, Richard D., Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142311/
https://ncbi.nlm.nih.gov/pubmed/21766412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.485
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