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Targeting of Nanoparticle-Complexed Drugs across the Vascular Endothelial Barrier via Caveolae

The endothelial cell monolayer lining the vessel wall forms a size-selective, semi-permeable barrier between the blood and tissue that must be crossed by blood borne therapeutic agents to reach diseased extravascular tissue. Nanoparticles engineered to carry drugs present an opportunity to enhance t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Zhenjia, Tiruppathi, Chinnaswamy, Cho, Jaehyung, Minshall, Richard D., Malik, Asrar B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142311/
https://ncbi.nlm.nih.gov/pubmed/21766412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.485
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