Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression

Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since numerous HERVs are epigenetically activated in tumors, their activat...

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Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Ito, Jumpei, Kimura, Izumi, Soper, Andrew, Coudray, Alexandre, Koyanagi, Yoshio, Nakaoka, Hirofumi, Inoue, Ituro, Turelli, Priscilla, Trono, Didier, Sato, Kei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577720/
https://ncbi.nlm.nih.gov/pubmed/33087347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3020
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