The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses

Retroviruses have been invading mammalian germlines for millions of years, accumulating in the form of endogenous retroviruses (ERVs) that account for nearly one-tenth of the mouse and human genomes. ERVs are epigenetically silenced during development, yet the cellular factors recognizing ERVs in a...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Wolf, Gernot, Yang, Peng, Füchtbauer, Annette C., Füchtbauer, Ernst-Martin, Silva, Andreia M., Park, Chungoo, Wu, Warren, Nielsen, Anders L., Pedersen, Finn S., Macfarlan, Todd S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358406/
https://ncbi.nlm.nih.gov/pubmed/25737282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252767.114
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