The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses

Retroviruses have been invading mammalian germlines for millions of years, accumulating in the form of endogenous retroviruses (ERVs) that account for nearly one-tenth of the mouse and human genomes. ERVs are epigenetically silenced during development, yet the cellular factors recognizing ERVs in a...

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Publicat a:Genes Dev
Autors principals: Wolf, Gernot, Yang, Peng, Füchtbauer, Annette C., Füchtbauer, Ernst-Martin, Silva, Andreia M., Park, Chungoo, Wu, Warren, Nielsen, Anders L., Pedersen, Finn S., Macfarlan, Todd S.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358406/
https://ncbi.nlm.nih.gov/pubmed/25737282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252767.114
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