The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses

Retroviruses have been invading mammalian germlines for millions of years, accumulating in the form of endogenous retroviruses (ERVs) that account for nearly one-tenth of the mouse and human genomes. ERVs are epigenetically silenced during development, yet the cellular factors recognizing ERVs in a...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Wolf, Gernot, Yang, Peng, Füchtbauer, Annette C., Füchtbauer, Ernst-Martin, Silva, Andreia M., Park, Chungoo, Wu, Warren, Nielsen, Anders L., Pedersen, Finn S., Macfarlan, Todd S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358406/
https://ncbi.nlm.nih.gov/pubmed/25737282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252767.114
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