Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression

Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since numerous HERVs are epigenetically activated in tumors, their activat...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Ito, Jumpei, Kimura, Izumi, Soper, Andrew, Coudray, Alexandre, Koyanagi, Yoshio, Nakaoka, Hirofumi, Inoue, Ituro, Turelli, Priscilla, Trono, Didier, Sato, Kei
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577720/
https://ncbi.nlm.nih.gov/pubmed/33087347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3020
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