Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression

Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since numerous HERVs are epigenetically activated in tumors, their activat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Ito, Jumpei, Kimura, Izumi, Soper, Andrew, Coudray, Alexandre, Koyanagi, Yoshio, Nakaoka, Hirofumi, Inoue, Ituro, Turelli, Priscilla, Trono, Didier, Sato, Kei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577720/
https://ncbi.nlm.nih.gov/pubmed/33087347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3020
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