Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression

Gene expression aberration is a hallmark of cancers, but the mechanisms underlying such aberrations remain unclear. Human endogenous retroviruses (HERVs) are genomic repetitive elements that potentially function as enhancers. Since numerous HERVs are epigenetically activated in tumors, their activat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Ito, Jumpei, Kimura, Izumi, Soper, Andrew, Coudray, Alexandre, Koyanagi, Yoshio, Nakaoka, Hirofumi, Inoue, Ituro, Turelli, Priscilla, Trono, Didier, Sato, Kei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2020
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577720/
https://ncbi.nlm.nih.gov/pubmed/33087347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3020
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