The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses

Retroviruses have been invading mammalian germlines for millions of years, accumulating in the form of endogenous retroviruses (ERVs) that account for nearly one-tenth of the mouse and human genomes. ERVs are epigenetically silenced during development, yet the cellular factors recognizing ERVs in a...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Wolf, Gernot, Yang, Peng, Füchtbauer, Annette C., Füchtbauer, Ernst-Martin, Silva, Andreia M., Park, Chungoo, Wu, Warren, Nielsen, Anders L., Pedersen, Finn S., Macfarlan, Todd S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358406/
https://ncbi.nlm.nih.gov/pubmed/25737282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252767.114
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