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The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses
Retroviruses have been invading mammalian germlines for millions of years, accumulating in the form of endogenous retroviruses (ERVs) that account for nearly one-tenth of the mouse and human genomes. ERVs are epigenetically silenced during development, yet the cellular factors recognizing ERVs in a...
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| Pubblicato in: | Genes Dev |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358406/ https://ncbi.nlm.nih.gov/pubmed/25737282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252767.114 |
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