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The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons

Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process transpires to be carefully regulated and is not an undirected, radical erasure of parental epigenomes. The TRIM28 complex has been shown to be crucia...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Seah, Michelle K. Y., Wang, Yaju, Goy, Pierre-Alexis, Loh, Hui Mun, Peh, Wen Jun, Low, Diana H. P., Han, Brenda Y., Wong, Esther, Leong, Ei Leen, Wolf, Gernot, Mzoughi, Slim, Wollmann, Heike, Macfarlan, Todd S., Guccione, Ernesto, Messerschmidt, Daniel M.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803371/
https://ncbi.nlm.nih.gov/pubmed/30846446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.170266
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