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The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons

Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process transpires to be carefully regulated and is not an undirected, radical erasure of parental epigenomes. The TRIM28 complex has been shown to be crucia...

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Vydáno v:Development
Hlavní autoři: Seah, Michelle K. Y., Wang, Yaju, Goy, Pierre-Alexis, Loh, Hui Mun, Peh, Wen Jun, Low, Diana H. P., Han, Brenda Y., Wong, Esther, Leong, Ei Leen, Wolf, Gernot, Mzoughi, Slim, Wollmann, Heike, Macfarlan, Todd S., Guccione, Ernesto, Messerschmidt, Daniel M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803371/
https://ncbi.nlm.nih.gov/pubmed/30846446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.170266
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