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KRAB-ZFP Repressors Enforce Quiescence of Oncogenic Human Herpesviruses

Cancer-causing herpesviruses infect nearly every human and persist indefinitely in B lymphocytes in a quiescent state known as latency. A hallmark of this quiescence or latency is the presence of extrachromosomal viral genomes with highly restricted expression of viral genes. Silencing of viral gene...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Li, Xiaofan, Burton, Eric M., Koganti, Siva, Zhi, Jizu, Doyle, Francis, Tenenbaum, Scott A., Horn, Biljana, Bhaduri-McIntosh, Sumita
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026741/
https://ncbi.nlm.nih.gov/pubmed/29695433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00298-18
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