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Cellular STAT3 Functions via PCBP2 To Restrain Epstein-Barr Virus Lytic Activation in B Lymphocytes

A major hurdle to killing Epstein-Barr virus (EBV)-infected tumor cells using oncolytic therapy is the presence of a substantial fraction of EBV-infected cells that does not support the lytic phase of EBV despite exposure to lytic cycle-promoting agents. To determine the mechanism(s) underlying this...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Koganti, Siva, Clark, Carissa, Zhi, Jizu, Li, Xiaofan, Chen, Emily I., Chakrabortty, Sharmistha, Hill, Erik R., Bhaduri-McIntosh, Sumita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403452/
https://ncbi.nlm.nih.gov/pubmed/25717101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00121-15
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