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Signal Transducer and Activator of Transcription 3 Limits Epstein-Barr Virus Lytic Activation in B Lymphocytes

Lytic activation of Epstein-Barr virus (EBV) is central to its life cycle and to most EBV-related diseases. However, not every EBV-infected B cell is susceptible to lytic activation. This lack of uniform susceptibility to lytic activation also directly impacts the success of viral oncolytic therapy...

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Autors principals: Hill, Erik R., Koganti, Siva, Zhi, Jizu, Megyola, Cynthia, Freeman, Alexandra F., Palendira, Umaimainthan, Tangye, Stuart G., Farrell, Paul J., Bhaduri-McIntosh, Sumita
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807321/
https://ncbi.nlm.nih.gov/pubmed/23966384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01762-13
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