Retrograde Regulation by the Viral Protein Kinase Epigenetically Sustains the Epstein-Barr Virus Latency-to-Lytic Switch To Augment Virus Production

Herpesviruses are ubiquitous, and infection by some, like Epstein-Barr virus (EBV), is nearly universal. To persist, EBV must periodically switch from a latent to a replicative/lytic phase. This productive phase is responsible for most herpesvirus-associated diseases. EBV encodes a latency-to-lytic...

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Vydáno v:J Virol
Hlavní autoři: Li, Xiaofan, Kozlov, Sergei V., El-Guindy, Ayman, Bhaduri-McIntosh, Sumita
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694827/
https://ncbi.nlm.nih.gov/pubmed/31189703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00572-19
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