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Assessing the Safety, Tolerability, Pharmacokinetics, and Biodistribution of Novel Oral Formulations of Amphotericin B following Single- and Multiple-Dose Administration to Beagle Dogs

The purpose of this study was to assess the safety, tolerability, pharmacokinetics (PK), and biodistribution of novel oral amphotericin B (AmpB) formulations following single- and multiple-oral-dose administration to healthy beagle dogs. The liquid formulation of AmpB was administered to three male...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Wasan, Kishor M., Wasan, Ellen K., Hnik, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577158/
https://ncbi.nlm.nih.gov/pubmed/32816728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01111-20
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