Efficacy, Biodistribution, and Nephrotoxicity of Experimental Amphotericin B-Deoxycholate Formulations for Pulmonary Aspergillosis

An experimental micellar formulation of 1:1.5 amphotericin B-sodium deoxycholate (AMB:DCH 1:1.5) was obtained and characterized to determine its aggregation state and particle size. The biodistribution, nephrotoxicity, and efficacy against pulmonary aspergillosis in a murine model were studied and c...

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發表在:Antimicrob Agents Chemother
Main Authors: López-Sánchez, Alicia, Pérez-Cantero, Alba, Torrado-Salmerón, Carlos, Martin-Vicente, Adela, García-Herrero, Víctor, González-Nicolás, María Ángeles, Lázaro, Alberto, Tejedor, Alberto, Torrado-Santiago, Santiago, García-Rodríguez, Juan José, Capilla, Javier, Torrado, Susana
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021657/
https://ncbi.nlm.nih.gov/pubmed/29760126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00489-18
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