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Pharmacokinetics of BMEDA after Intravenous Administration in Beagle Dogs

The pharmacokinetics of N,N-bis(2-mercapatoethly)-N',N'-diethylenediamine (BMEDA), a molecule that can form a chelate with rhenium-188 ((188)Re) to produce the (188)Re-BMEDA-liposomes, was studied. In this work, beagles received a single injection of BMEDA, at doses of 1, 2, or 5 mg/kg; th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chang, Chih-Hsien, Liu, Si-Yen, Lee, Te-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271955/
https://ncbi.nlm.nih.gov/pubmed/24394437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19010538
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