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Effects of Lipid-Based Oral Formulations on Plasma and Tissue Amphotericin B Concentrations and Renal Toxicity in Male Rats

The purpose of this study was to determine the effects of various lipid and mixed-micelle formulations on the oral absorption and renal toxicity of amphotericin B (AMB) in rats. The maximum concentration of AMB in plasma and the area under the concentration-time curve for 0 to 24 h for AMB were elev...

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Detalhes bibliográficos
Main Authors: Risovic, Verica, Boyd, Michael, Choo, Eugene, Wasan, Kishor M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC201114/
https://ncbi.nlm.nih.gov/pubmed/14506053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3339-3342.2003
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