Tropically stable novel oral lipid formulation of amphotericin B (iCo-010): biodistribution and toxicity in a mouse model

BACKGROUND: The purpose of this study was to evaluate the biodistribution and toxicity of amphotericin B (AmB) following multiple oral administrations of a novel tropically stable lipid-based formulation (iCo-010). METHODS: BALB/c mice were allocated into six groups: oral iCo-010 twice daily for 5 d...

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Main Authors: Sivak, Olena, Gershkovich, Pavel, Lin, Molly, Wasan, Ellen K, Zhao, Jinying, Owen, David, Clement, John G, Wasan, Kishor M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162910/
https://ncbi.nlm.nih.gov/pubmed/21824435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-135
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