In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines

BACKGROUND: Invasive fungal infections such as candidiasis constitute an increasingly important medical problem. Drugs currently used for the treatment of candidiasis include polyenes (such as Amphotericin B) and azoles. Amphotericin B (AmpB) presents several limitations such as its nephrotoxicity a...

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Detalhes bibliográficos
Main Authors: Leon, Carlos G, Lee, Jinkyung, Bartlett, Karen, Gershkovich, Pavel, Wasan, Ellen K, Zhao, Jinying, Clement, John G, Wasan, Kishor M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173361/
https://ncbi.nlm.nih.gov/pubmed/21854638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-144
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