HIF-1α-Mediated, NADPH Oxidase-Derived ROS Contributes to Laryngeal Airway Hyperreactivity Induced by Intermittent Hypoxia in Rats

Obstructive sleep apnea, similar to intermittent hypoxia (IH) during sleep, is associated with laryngeal airway hyperreactivity (LAH). IH-induced laryngeal oxidative stress may contribute to LAH, but the underlying mechanism remains unknown. Conscious rats were subjected to repetitive 75 s cycles of...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autors principals: Lin, You Shuei, Shen, Yan-Jhih, Ou, Ping-Hsun, Lai, Ching Jung
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575773/
https://ncbi.nlm.nih.gov/pubmed/33117193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.575260
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