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The Role of NADPH Oxidase in Chronic Intermittent Hypoxia-Induced Pulmonary Hypertension in Mice

Obstructive sleep apnea, characterized by intermittent periods of hypoxemia, is an independent risk factor for the development of pulmonary hypertension. However, the exact mechanisms of this disorder remain to be defined. Enhanced NADPH oxidase expression and superoxide (O(2)(−)·) generation in the...

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Autors principals: Nisbet, Rachel E., Graves, Anitra S., Kleinhenz, Dean J., Rupnow, Heidi L., Reed, Alana L., Fan, Tai-Hwang M., Mitchell, Patrick O., Sutliff, Roy L., Hart, C. Michael
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677439/
https://ncbi.nlm.nih.gov/pubmed/18952568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0145OC
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