Hypoxia-Inducible Factor 1 Mediates Increased Expression of NADPH Oxidase-2 in Response to Intermittent Hypoxia

Sleep-disordered breathing with recurrent apnea is associated with intermittent hypoxia (IH). Cardiovascular morbidities caused by IH are triggered by increased generation of reactive oxygen species (ROS) by pro-oxidant enzymes, especially NADPH oxidase-2 (Nox2). Previous studies showed that (i) IH...

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Publicat a:J Cell Physiol
Autors principals: Yuan, Guoxiang, Khan, Shakil A., Luo, Weibo, Nanduri, Jayasri, Semenza, Gregg L., Prabhakar, Nanduri R.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695992/
https://ncbi.nlm.nih.gov/pubmed/21302291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22640
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